Palestinians gather during a protest at the Gaza Strip's border with Israel, Friday, April 27, 2018. Palestinians converged on the Gaza border with Israel for a fifth round of weekly protests Friday, some throwing stones and burning tires, as a top U.N. official urged Israel to refrain from using excessive force against them. (AP Photo/ Khalil Hamra)
Palestinians gather during a protest at the Gaza Strip's border with Israel, Friday, April 27, 2018. Palestinians converged on the Gaza border with Israel for a fifth round of weekly protests Friday, some throwing stones and burning tires, as a top U.N. official urged Israel to refrain from using excessive force against them. (AP Photo/ Khalil Hamra) Credit: ap — Khalil Hamra

Gaza City, Gaza Strip — Hundreds of Palestinians converged on the Gaza Strip’s border fence with Israel on Friday, trying to rip through it before drawing heavy Israeli fire in one of the most violent incidents yet in five weeks of protests. Three Palestinians were killed and dozens were reported wounded.

The violence came shortly after a top U.N. official urged Israel to refrain from using excessive force against the protesters.

At least 38 protesters have been killed by Israeli live fire and more than 1,600 wounded in the weekly protests since they began March 30. Israel has rejected the international criticism, saying it is defending its sovereign border and accusing Gaza’s Hamas leaders, who are organizing the protests, of using the crowds as cover to carry out attacks.

In Friday’s unrest, a large crowd gathered a few hundred yards from the border, with some throwing stones and setting tires on fire in what has become a weekly occurrence.

Late in the afternoon, dozens of young men broke away from the larger protest, moving south about 200 yards and approaching the fence. The crowd then tried to break through the fence with wire cutters when Israeli forces opened fire. Witnesses said three protesters briefly crossed into Israel and turned around.

Hundreds of additional protesters ran to the scene, and the numbers quickly grew to several thousand. Israeli armored vehicles sped to the site and fired barrages of tear gas. As gunfire erupted, the crowd dispersed. A dozen Palestinian ambulances jammed a dirt road lining up to evacuate the wounded. Some in the crowd shouted “shahid,” or “martyr” as bodies were taken away on stretchers.

Palestinian health officials reported three people killed and 611 wounded, including 138 hit by live fire in incidents along the border throughout the day.

Israeli military said it had “thwarted” an attempted infiltration by Palestinian protesters.

It said “hundreds of rioters” tried to burn the fence and enter the Israel. It said the crowd threw explosives, firebombs and rocks, and that troops opened fire “in accordance with the rules of engagement” and halted the crowd. It released a video showing a young Palestinian man placing a burning tire along the fence in an apparent attempt to set it on fire. In another, a small group lobs stones at an Israeli military vehicle on the other side of the fence.

In other incidents, the military said Palestinian crowds rolled burning tires, hurled rocks and flew kites with flaming objects attached with the goal of damaging the fence and other Israeli targets. It also released a photo appearing to show a group of youths tugging at barbed wire along the fence.

The marches, aimed in part at trying to break a decade-old border blockade, have been organized by Gaza’s militant Hamas rulers but have also been driven by widespread despair in the coastal territory of 2 million people.

Gaza organizers say the marches are also pressing for the “right of return” of refugees and their descendants to what is now Israel.

Two-thirds of Gaza residents are descendants of refugees who fled or were expelled from properties during the war surrounding Israel’s creation in 1948. The protests are to culminate on May 15, the anniversary of Israel’s creation. Hamas organizers have made conflicting statements about whether they plan a mass border breach at some point.

Hamas’ supreme leader, Ismail Haniyeh, visited a protest camp in the southern town of Rafah, and vowed of larger protests to come in Gaza.