Toronto Blue Jays' Russell Martin (55) is tagged out by Los Angeles Angels shortstop Andrelton Simmons (2) as he is caught in a rundown during the fourth inning of a baseball game Tuesday, May 22, 2018, in Toronto. (Frank Gunn/The Canadian Press via AP)
Toronto Blue Jays' Russell Martin (55) is tagged out by Los Angeles Angels shortstop Andrelton Simmons (2) as he is caught in a rundown during the fourth inning of a baseball game Tuesday, May 22, 2018, in Toronto. (Frank Gunn/The Canadian Press via AP) Credit: Frank Gunn

Chicago — Jose Ramirez hit his 14th homer and the Clveland Indians routed the Cubs, 10-1, on Tuesday night in their first meeting at Wrigley Field since the 2016 World Series.

The AL Central leaders moved back to .500 with an easy victory against the team that beat them two years ago to end a 108-year championship drought.

Ramirez got the blowout going with his three-run drive in the third. The Indians scored four times in the inning while chasing a wild Tyler Chatwood (3-4).

Trevor Bauer (4-3) went six innings in his second straight scoreless start. The right-hander gave up seven hits and struck out six.

Yonder Alonso had three of Cleveland’s 11 hits, including a three-run double in the fifth.

Chicago’s Ian Happ led off the ninth with a pinch-hit homer against Josh Tomlin.

Blue Jays 5, Angels 3

Toronto — Kendrys Morales hit a two-run home run, J.A. Happ won his second straight start and the Toronto burst to a five-run first-inning lead in a win over Los Angeles Angels that stopped a four-game losing streak.

Josh Donaldson had two doubles and Teoscar Hernandez singled home the first run as the Blue Jays ended a six-game home skid and won for the fourth time in 16 games at Rogers Centre.

Los Angeles has lost eight of 11.

Marlins 5, Mets 1

New York — Caleb Smith pitched neatly into the seventh inning against a Mets lineup that included newcomer Jose Bautista, leading Miami over New York.

Derek Dietrich homered and J.T. Realmuto got three hits as Miami, the lowest-scoring team in the majors, ended a three-game skid. The Mets had won four in a row.

Smith (3-5) pitched with poise, giving up three hits over 6⅔ innings. The lefty fanned eight, including Bautista twice, and leads major league rookies with 65 strikeouts.

Nationals 2, Padres 1

Washington — Bryce Harper hit his NL leading 15th home run of the season and Michael Taylor’s one-out double in the ninth scored the game-winning run as Washington defeated San Diego.

Juan Soto, the youngest player in the majors, reached base in all four at-bats in his second career start. The 19-year-old led off the ninth with his third walk, took second on Wilmer Difo’s groundout and scored on Taylor’s hit off the center-field wall against Matt Strahm (0-2).

Braves 3, Phillies 1

Philadelphia — Ozzie Albies hit his 14th homer and Brandon McCarthy tossed 5⅔ sharp innings, leading Atlanta to the victory.

McCarthy (5-2) allowed one run and four hits. He is 4-0 with a 2.08 ERA against Philadelphia this season and 1-2 with a 6.60 ERA against the rest of the league.

Vince Velasquez (4-5) gave up two runs — one earned — and fanned nine in 4⅔ innings. He fell to 0-4 against the Braves.

Brewers 1, Diamondbacks 0

Milwaukee — Jhoulys Chacin and three relievers combined on a three-hitter as Milwaukee slipped past slumping Arizona.

Domingo Santana drove in the only run with a sacrifice fly in the sixth inning for the NL Central leaders. Milwaukee (30-19) moved a season-high 11 games over .500, while the Diamondbacks have lost six in a row and 12 of 13 — scoring just 24 runs in that stretch.

Reds 7, Pirates 2

Cincinnati— Matt Harvey pitched six innings of one-run ball for his first victory with Cincinnati and Scooter Gennett hit his fifth grand slam over the last two seasons.

Harvey (1-2) gave up three hits in his third start for the Reds, who acquired him from the Mets for catcher Devin Mesoraco on May 8. So far, he’s making good on his second chance, throwing more pitches in each outing as he gets back into form after being relegated to the Mets bullpen.

Royals 5, Cardinals 1

St. Louis — Alex Gordon and Salvador Perez each homered and Jason Hammel earned his first victory of the season as Kansas City beat St. Louis.

Hammel (1-5) has been winless in his previous 13 starts dating back to his last win on Sept. 6, 2017.

Hammel also had been winless in his previous seven road starts.