Detroit Tigers third baseman Nick Castellanos bare-hands a grounder before throwing out Toronto Blue Jays' Devon Travis at first base during the ninth inning of a baseball game Tuesday, June 7, 2016, in Detroit. (AP Photo/Duane Burleson)
Detroit Tigers third baseman Nick Castellanos bare-hands a grounder before throwing out Toronto Blue Jays' Devon Travis at first base during the ninth inning of a baseball game Tuesday, June 7, 2016, in Detroit. (AP Photo/Duane Burleson)

Baltimore— Kansas City right-hander Yordano Ventura hit Manny Machado with a pitch to spark a bench-emptying fray, and the Baltimore Orioles extended the Royals’ losing streak to a season-high six games with a 9-1 rout Tuesday night.

Mark Trumbo homered and drove in four runs, and the Orioles also got long balls from Ryan Flaherty, Chris Davis and Adam Jones.

But the game’s most striking moment came in the fifth, when Ventura (4-4) drilled Machado in the back with a 99 mph fastball. In the second inning, with Baltimore leading 5-0, the two exchanged words after Ventura twice threw inside to the two-time All-Star.

So in the fifth, an instant after the ball hit him, Machado charged the mound. Ventura prepared for the onslaught by slinging aside his cap and glove, but Machado landed a solid punch before the pitcher tackled him to the ground.

Both dugouts and bullpens emptied before peace was restored. Machado was restrained by teammate Chris Tillman after the initial thrust.

Machado and Ventura were ejected.

Tigers 3, Blue Jays 2 (10)

Detroit — Ian Kinsler drove in the winning run with a 10th-inning single, and Detroit won its fifth straight game.

The Tigers tied it with two runs in the ninth, spoiling an outstanding effort by Blue Jays starter Aaron Sanchez. The right-hander struck out a career-high 12 and took a one-hitter into the ninth inning, but he didn’t get another out as Detroit rallied.

Kinsler’s RBI double in the ninth chased Sanchez, and Miguel Cabrera’s one-out double off Roberto Osuna tied it.

The Tigers loaded the bases in the 10th with no outs against Joe Biagini (3-2), and Kinsler won it with a chopper into left field.

Justin Wilson (2-1) pitched a scoreless 10th for the win.

Reds 7, Cardinals 6

Cincinnati — Joey Votto homered with one out in the bottom of the ninth inning, powering Cincinnati over St. Louis after it blew a five-run lead for the second straight day.

Votto connected off left-hander Kevin Siegrist (4-1) for his fifth career game-ending homer and Cincinnati’s third homer of the game.

Left-hander John Lamb shut down the Cardinals with his 65 mph curveball, allowing only one earned run in a career-high 7 innings.

Pirates 3, Mets 1Pirates 3, Mets 1

Pittsburgh — Juan Nicasio retired his first 12 batters and got his second win in six starts, and Pittsburgh beat New York to complete a doubleheader sweep.

The Pirates also won the first game 3-1 behind seven scoreless innings from Jon Niese (6-2) against his former team. Josh Harrison had three hits and Jordy Mercer hit his first home run at PNC Park since Aug. 31, 2014 in the first victory.

Nicasio (5-4) allowed a run on three hits and two walks over five innings. He had gone 1-2 with a 6.23 ERA in his previous five starts, and manager Clint Hurdle acknowledged last week that he was considering moving the right-hander to the bullpen.

Jacob deGrom (3-2) is winless in his last seven starts after he allowed three runs in six innings with nine strikeouts and no walks. He has not won since April 30 against San Francisco despite allowing three earned runs or fewer six times.

The Pirates snapped left-hander Steven Matz’s (7-2) seven-game winning streak in the first game.

Yankees 6, Angels 3

New York — Carlos Beltran and Starlin Castro homered for the second consecutive game, sending a resurgent Michael Pineda and New York past Los Angeles.

Pineda (3-6) threw 22 of 27 first-pitch strikes and tossed seven efficient innings in his longest start since July 4 last year at Tampa Bay. He gave up three runs and four hits, building on a solid performance last week in Detroit after struggling for much of the season.

With his past two outings, the enigmatic right-hander has quieted talk about him losing his spot in the rotation and perhaps getting sent to the minors.

Phillies 3, Cubs 2

Philadelphia — Jerad Eickhoff threw seven impressive innings, Ryan Howard hit a solo homer and Philadelphia beat Chicago.

Eickhoff (3-8) allowed one run and two hits, striking out eight. Jeanmar Gomez pitched out of a bases-loaded jam in the eighth and got the final six outs for his 19th save in 20 tries.

Former Dartmouth pitcher Kyle Hendricks (4-5) gave up two runs and four hits, striking out six in five innings.

Brewers 5, Athletics 4

Milwaukee— Zach Davies took a no-hitter into the seventh before allowing a two-out home run to Oakland’s Billy Butler, and Milwaukee withstood a shaky ninth inning.

Davies (4-3) allowed two hits and three walks over seven innings while striking out five. Butler turned on an 0-1 fastball from Davies to end the shutout.

The A’s mounted their best rally in the ninth against closer Jeremy Jeffress after getting runners on second and third while trailing by three.

Rangers 4, Astros 3

Arlington, Texas — Ian Desmond hit a tiebreaking two-run homer in the eighth inning and the Rangers extended their dominance of Houston.

The Rangers are 8-0 this year against their AL West and instate rivals and have won 12 straight in Arlington against the Astros. The only longer Texas streak in Arlington against one team was a 15-game run against the New York Yankees from 1989-91.

Desmond’s one-out drive was just over the glove of leaping center fielder Carlos Gomez and came off 2015 AL Cy Young Award winner Dallas Keuchel (3-8). It tagged the bearded the left-hander with as many losses as he had all last season while winning 20 games.