Ohio State quarterback J.T. Barrett looks to throw against Michigan State during the fourth quarter half of an NCAA college football game, Saturday, Nov. 19, 2016, in East Lansing, Mich. Ohio State won 17-16. (AP Photo/Al Goldis)
Ohio State quarterback J.T. Barrett looks to throw against Michigan State during the fourth quarter half of an NCAA college football game, Saturday, Nov. 19, 2016, in East Lansing, Mich. Ohio State won 17-16. (AP Photo/Al Goldis) Credit: Al Goldis

East Lansing, Mich. — Mike Weber ran for 111 yards and a touchdown, and No. 2 Ohio State held off Michigan State, 17-16, on Saturday after the Spartans missed a 2-point conversion with 4:41 remaining.

Ohio State (10-1, 7-1 Big Ten, No. 2 CFP) can now move on to next weekend’s showdown with rival Michigan, but only after withstanding a spirited challenge from a Michigan State team that derailed the Buckeyes’ national title bids in two of the previous three seasons. The Spartans (3-8, 1-7) were down 17-10 when LJ Scott scored on a 1-yard run with 4:41 to play. Michigan State went for the lead, but Tyler O’Connor’s pass on the 2-point conversion attempt was intercepted in the end zone.

Michigan State coach Mark Dantonio said he’d planned all week for the Spartans to go for 2 if a situation like that came up.

The Spartans got the ball back one more time, at their own 20 with 2:04 remaining. Tyquan Lewis sacked O’Connor on the first play, and then Gareon Conley intercepted him on the second.

No. 4 Michigan 20, Indiana 10

Ann Arbor, Mich. — De’Veon Smith ran for two touchdowns in a 3:33 span late in the third quarter, finishing with a career-high 158 yards rushing, to help Michigan shake off Indiana.

John O’Korn made his first start for Michigan (10-1, 7-1, No. 3 CFP), replacing the injured Wilton Speight, and struggled to lead an offense that was averaging 45 points and 232 yards passing.

No. 6 Wisconsin 49, Purdue 20

West Lafayette, Ind. — T.J. Watt returned an interception 17 yards for a touchdown, and Wisconsin scored 35 points in the final 8½ minutes of the first half.

Alec Ingold and Bradrick Shaw each scored twice during the flurry, helping the Badgers (9-2, 6-2 Big Ten, No. 7 CFP) to their fifth straight win overall and 11th in a row in the series. They can wrap up the West Division title and earn a spot in the conference championship game with a victory next weekend at home against Minnesota.

Oregon 30, No. 11 Utah 28

Salt Lake City — Justin Herbert threw a 17-yard touchdown pass to Darren Carrington with 2 seconds remaining to lift Oregon past Utah, putting the Utes’ Pac-12 championship hopes in jeopardy.

Herbert led the Ducks (4-7, 2-6) on a 10-play, 75-yard drive in just over two minutes, capping it with the TD pass to Carrington. Carrington was initially called out of bounds but that call was reversed after a replay showed he got a foot down inbounds.

No. 12 Colorado 38No. 20 Washington State 24

Boulder, Colo. — Sefo Liufau threw for 345 yards, ran for 108 more and scored three touchdowns in Colorado’s victory over Washington State in a matchup of unlikely Pac-12 division leaders.

Phillip Lindsay added 144 yards rushing and two TDs for the Buffaloes (9-2, 7-1, No. 10 CFP).

No. 13 Oklahoma State 31, TCU 6

Fort Worth, Texas — Mason Rudolph ran for two touchdowns and threw for another score AND Oklahoma State earned a Big 12 title shot with its seventh consecutive victory.

The Cowboys (9-2, 7-1, No. 11 CFP) will be conference champions if they beat No. 8 Oklahoma in their regular-season finale after an open date.

No. 14 Western Michigan 38Buffalo 0

Kalamazoo, Mich. — Zach Terrell passed for a career-high 445 yards and four touchdowns, helping Western Michigan remain undefeated.

Corey Davis had 13 catches for 173 yards and two touchdowns, breaking the Mid-American Conference record for career receptions.

No. 21 Florida 16, No. 16 LSU 10

Baton Rouge, La. — Florida stuffed LSU’s Derrius Guice on a do-or-die run from the 1 in the final seconds and the Gators held on to wrap up the Southeastern Conference’s East Division.

The stop capped a defensive struggle in which LSU converted a fourth-and-10 play on its final drive, only to get stopped on back-to-back runs from the 1 to end the game.

No. 17 Florida State 45, Syracuse 14

Syracuse, n.y. — Dalvin Cook ran for 225 yards and four touchdowns to become Florida State’s career rushing leader.

Cook entered the game needing 19 yards to break Warrick Dunn’s 20-year old school record for rushing (3,959) and did so with a 41-yarder in the first quarter.

No. 19 Nebraska 28, Maryland 7

Lincoln, Neb. — Terrell Newby ran for a career-high three touchdowns for Nebraska, and Ryker Fyfe passed for 220 yards and a score filling in for injured starter Tommy Armstrong Jr.

The Cornhuskers (9-2, 6-2 Big Ten) stayed alive in the West Division. They must win at Iowa on Friday and Wisconsin must lose to Minnesota for Nebraska to go to the conference championship game.

No. 23 Texas A&M 23, UTSA 10

College Station, Texas — Jake Hubenak threw for 248 yards and a touchdown and Myles Garrett had 4½ sacks to help No. 23 Texas A&M get back on track.

The Aggies (8-3) were in desperate need of a victory after consecutive losses to Mississippi State and Mississippi ruined their shot at the College Football Playoff.

Wyoming 34, No. 24 San Diego St. 33

Laramie, Wyo. — Josh Allen threw two touchdown passes, including a 29-yarder to C.J. Johnson with 1:07 left, and Wyoming stopped a 2-point conversion attempt by San Diego State with no time on the clock.

Allen completed 16 of 31 passes for 282 yards and also rushed for 56 yards. Brian Hill added 131 yards on 31 carries and two TDs for the Cowboys (8-3, 6-1 Mountain West). Johnson had five catches for 85 yards.