Chicago — Jake Arrieta’s bid for a second straight no-hitter ended after five pitches and the Cubs ace went on to win his 16th straight decision, leading Chicago over the Milwaukee Brewers 7-2 Thursday.

Arrieta (5-0) gave up one run, three hits and four walks in five innings — the first run he allowed at Wrigley Field since July 25. Alex Presley’s fifth-inning RBI double ended Arrieta’s home scoreless streak at 52 innings, four outs shy of the big league record.

At 16-5, Chicago is off to its best 21-game start since 1907.

Ben Zobrist hit a two-run single in the first off Taylor Jungmann (0-4), who gave up five runs, six hits and three walks in 3 innings.

Phillies 3, Nationals 0

Washington — Cameron Rupp hit a tiebreaking, two-run double off Jonathan Papelbon in a three-run ninth, and Philadelphia completed a three-game sweep.

Aaron Nola, Dalier Hinojosa, Elvis Araujo (1-0) and Jeanmar Gomez combined on a four-hitter and extended Washington’s scoreless streak to 22 innings.

Odubel Herrera singled off Felipe Rivero (0-1) opening the ninth and took third on Freddy Galvis’ double.

Maikel Franco was walked intentionally, and Papelbon came in to strike out pinch-hitter Darin Ruf. Rupp hit a drive that landed over a backpedaling Bryce Harper at the warning track in right, and David Lough followed with a run-scoring single.

Tigers 7, Athletics 3

Detroit — Anthony Gose doubled and homered, and Anibal Sanchez (3-2) allowed two runs and three hits in 5 innings. Sanchez struck out nine, but walked seven — one shy of his big league high.

Chris Bassitt (0-2) gave up seven runs, 10 hits and three walks in 3 innings as Oakland lost for the fifth time in six games.

Francisco Rodriguez got one out for his fifth save.

Orioles 10, White Sox 2

Baltimore — Manny Machado had a grand slam and a career-high five RBIs, leading Baltimore over the White Sox and stopping Chicago’s six-game winning streak.

Chris Davis and Mark Trumbo hit consecutive third-inning homers for the Orioles, whose 8-1 record at Camden Yards is the best home mark in the major leagues.

Machado stopped an 0-for-17 slide with an RBI double in a four-run third inning against John Danks (0-4) and homered in the sixth off Jake Petricka. Machado is batting .333 with a team-high seven homers.

Notes Saves Leader Put On Bereavement List

Baltimore — White Sox closer David Robertson will miss at least three games after being placed on the bereavement list before Thursday’s series opener at Baltimore because of the death of his father-in-law.

Robertson leads the AL with eight saves. He has an 0.87 ERA with 13 strikeouts and a .152 (5-33) opponents’ batting average.

The Brewers placed second baseman Scooter Gennett on the 15-day disabled list with right oblique tightness.